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6 The phosphodiesterase-5 inhibitor sildenafil is certified for PAH in FC I–IV from the United states and FC II–III in Europe. Endothelin receptor antagonists (ERAs) together with bosentan, sitaxentan and ambrisentan are oral therapies licensed for use in PAH. As no oral agent has shown superiority there continues to be https://rivereijlj.vidublog.com/25709093/top-bosentan-secrets

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