The reverse transcriptase also has ribonuclease activity that degrades the viral RNA throughout the synthesis of cDNA, in addition to DNA-dependent DNA polymerase activity that produces a sense DNA from your antisense cDNA.[69] With each other, the cDNA and its complement form a double-stranded viral DNA which is then transported https://hivhub.in/hiv-epidemic-in-india-trends-and-state-wise-distribution/