This refers to how an allosteric modulator affects signaling for a certain orthosteric agonist. Such as, an allosteric modulator may alter THC signaling, although not endogenous cannabinoid signaling. A crucial possible endogenous unfavorable allosteric modulator for CB1 will be the steroid hormone, pregnenolone [40–42]. Some (even though not all [43–forty https://injury-settlement-process12222.full-design.com/fascination-about-cannabis-strains-75272323