Contraindicated (one)pentobarbital will decrease the extent or effect of cariprazine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. CYP3A4 is liable for the formation and elimination of cariprazine's active metabolites. pentobarbital and olopatadine intranasal each increase sedation. Avoid or Use Alternate Drug. Coadministration raises hazard of CNS despair... https://hught716yjq0.wikififfi.com/user