This gain would therefore be important for patient safety in vivo if conolidine were to be validated in people. use - habitually do a thing (use only in the past tense); "She accustomed to contact her mother each and every 7 days but now she calls only at times"; https://brooksknkys.thezenweb.com/new-step-by-step-map-for-how-to-use-conolidine-76093212